Usually means: Roll a marijuana cigarette tightly.
Definitions Related words Mentions
We found 6 dictionaries that define the word skin up:

General (4 matching dictionaries)
  1. skin up: Longman Dictionary of Contemporary English
  2. skin up: Collins English Dictionary
  3. skin up: Wiktionary
  4. skin up: TheFreeDictionary.com

Slang (2 matching dictionaries)
  1. skin up: English slang and colloquialisms used in the United Kingdom
  2. skin up: Urban Dictionary

Definitions from Wiktionary (skin up)

verb:  (slang, intransitive) To make a cannabis cigarette.

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