Usually means: Proteins involved in cellular regulation.
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We found 3 dictionaries that define the word sirtuin:

General (3 matching dictionaries)
  1. Sirtuin, sirtuin: Wordnik
  2. sirtuin: Wiktionary
  3. Sirtuin: Wikipedia, the Free Encyclopedia

Definitions from Wiktionary (sirtuin)

noun:  (biochemistry) Any of several enzymes that act as regulatory factors that mediate the life-extending effects of a low-calorie diet.

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