Usually means: Partially natural, partially man-made.
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We found 18 dictionaries that define the word semisynthetic:

General (13 matching dictionaries)
  1. semisynthetic: Merriam-Webster
  2. semisynthetic: Oxford Learner's Dictionaries
  3. semisynthetic: American Heritage Dictionary of the English Language
  4. semisynthetic: Collins English Dictionary
  5. semisynthetic: Vocabulary.com
  6. semisynthetic: Wordnik
  7. semisynthetic: Wiktionary
  8. semisynthetic: Infoplease Dictionary
  9. semisynthetic: Dictionary.com
  10. semisynthetic: Rhymezone
  11. semisynthetic: FreeDictionary.org
  12. semisynthetic: Mnemonic Dictionary
  13. semisynthetic: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. semisynthetic: Encyclopedia

Medicine (4 matching dictionaries)
  1. semisynthetic: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. online medical dictionary (No longer online)
  4. semisynthetic: Medical dictionary

Definitions from Wiktionary (semisynthetic)

adjective:  (organic chemistry) synthesized by chemically modifying a natural material
noun:  (organic chemistry) Any compound that is synthesized by chemically modifying a natural material.

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