Usually means: Electrosurgical device for cutting tissue.
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We found 5 dictionaries that define the word radio knife:

General (3 matching dictionaries)
  1. radio knife: Wiktionary
  2. radio knife: Infoplease Dictionary
  3. radio knife: Dictionary.com

Computing (1 matching dictionary)
  1. radio knife: Encyclopedia

Medicine (1 matching dictionary)
  1. radio knife: Merriam-Webster Medical Dictionary

Definitions from Wiktionary (radio knife)

noun:  (medicine) A surgical instrument that uses a high-frequency electric arc to cut through or cut away tissue and at the same time sterilize the edges of the wound and seal cut blood vessels.

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