We found one dictionary that defines the word puke one's brains out:

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1. puke one's brains out: Wiktionary

Definitions from Wiktionary (puke one's brains out) ▸ verb:  (slang) To vomit violently. ▸ Words similar to puke one's brains out ▸ Usage examples for puke one's brains out ▸ Idioms related to puke one's brains out ▸ Wikipedia articles (New!) ▸ Words that often appear near puke one's brains out ▸ Rhymes of puke one's brains out ▸ Invented words related to puke one's brains out