Usually means: Surgical removal of rectum, sigmoid.
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We found 7 dictionaries that define the word proctosigmoidectomy:

General (2 matching dictionaries)
  1. proctosigmoidectomy: Wiktionary
  2. proctosigmoidectomy: Dictionary.com

Computing (1 matching dictionary)
  1. proctosigmoidectomy: Encyclopedia

Medicine (4 matching dictionaries)
  1. proctosigmoidectomy: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. online medical dictionary (No longer online)
  4. proctosigmoidectomy: Medical dictionary

Definitions from Wiktionary (proctosigmoidectomy)

noun:  (surgery) Complete or partial excision of the rectum and sigmoid colon.

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