Usually means: Wild plant, bitter, milky sap.
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We found 10 dictionaries that define the word prickly lettuce:

General (9 matching dictionaries)
  1. prickly lettuce: Merriam-Webster
  2. prickly lettuce: Vocabulary.com
  3. prickly lettuce: Dictionary.com
  4. Prickly lettuce: Wikipedia, the Free Encyclopedia
  5. prickly lettuce: Rhymezone
  6. prickly lettuce: FreeDictionary.org
  7. prickly lettuce: Mnemonic Dictionary
  8. prickly lettuce: TheFreeDictionary.com
  9. prickly lettuce: Wiktionary

Medicine (1 matching dictionary)
  1. prickly lettuce: Medical dictionary

Definitions from Wiktionary (prickly lettuce)

noun:  Lactuca serriola, an annual or biennial plant in the dandelion tribe within the daisy family, the closest wild relative of cultivated lettuce.

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