Usually means: Period before puberty begins biologically.
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We found 13 dictionaries that define the word prepubescence:

General (8 matching dictionaries)
  1. prepubescence: Merriam-Webster
  2. prepubescence: Oxford Learner's Dictionaries
  3. prepubescence: American Heritage Dictionary of the English Language
  4. prepubescence: Collins English Dictionary
  5. prepubescence: Wiktionary
  6. prepubescence: Dictionary.com
  7. Prepubescence: Wikipedia, the Free Encyclopedia
  8. prepubescence: TheFreeDictionary.com

Business (2 matching dictionaries)
  1. prepubescence: Legal dictionary
  2. prepubescence: Financial dictionary

Computing (1 matching dictionary)
  1. prepubescence: Encyclopedia

Medicine (2 matching dictionaries)
  1. prepubescence: Merriam-Webster Medical Dictionary
  2. prepubescence: Medical dictionary

Definitions from Wiktionary (prepubescence)

noun:  The period prior to the onset of puberty; prepuberty

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