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We found 2 dictionaries that define the word poyson:

General (2 matching dictionaries)
  1. Poyson, poyson: Wordnik
  2. poyson: Wiktionary

Definitions from Wiktionary (Poyson)

noun:  Obsolete spelling of poison. [A substance that is harmful or lethal to a living organism when ingested.]
verb:  Obsolete spelling of poison. [(transitive) To use poison to kill or paralyse (somebody).]

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