Usually means: Birthmark resembling a wine stain.
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We found 8 dictionaries that define the word port-wine mark:

General (3 matching dictionaries)
  1. port-wine mark: Wordnik
  2. port-wine mark: Wiktionary
  3. port-wine mark: TheFreeDictionary.com

Business (1 matching dictionary)
  1. port-wine mark: Legal dictionary

Computing (1 matching dictionary)
  1. port-wine mark: Encyclopedia

Medicine (3 matching dictionaries)
  1. port-wine mark: Merriam-Webster Medical Dictionary
  2. online medical dictionary (No longer online)
  3. port-wine mark: Medical dictionary

Definitions from Wiktionary (port-wine mark)

noun:  (anatomy) naevus flammeus

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