Usually means: Large protein cleaved into fragments.
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We found 8 dictionaries that define the word polyprotein:

General (3 matching dictionaries)
  1. polyprotein: Wiktionary
  2. polyprotein: Dictionary.com
  3. Polyprotein: Wikipedia, the Free Encyclopedia

Medicine (5 matching dictionaries)
  1. polyprotein: Merriam-Webster Medical Dictionary
  2. online medical dictionary (No longer online)
  3. Hepatitis C Information Central (No longer online)
  4. AIDS Medical Glossary and Drug Chart (No longer online)
  5. Glossary of HIV/AIDS Related Terms (No longer online)

Definitions from Wiktionary (polyprotein)

noun:  (biochemistry) Any protein (especially ones produced by viruses) that cleave to produce a number of polypeptides, some of which act as hormones

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