Usually means: Harmful effect with subtle onset.
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We found 17 dictionaries that define the word perniciousness:

General (13 matching dictionaries)
  1. perniciousness: Merriam-Webster
  2. perniciousness: Oxford Learner's Dictionaries
  3. perniciousness: Collins English Dictionary
  4. perniciousness: Vocabulary.com
  5. perniciousness: Wordnik
  6. perniciousness: Wiktionary
  7. perniciousness: Dictionary.com
  8. Perniciousness: Wikipedia, the Free Encyclopedia
  9. perniciousness: Rhymezone
  10. perniciousness: Webster's 1828 Dictionary
  11. perniciousness: FreeDictionary.org
  12. perniciousness: Mnemonic Dictionary
  13. perniciousness: TheFreeDictionary.com

Business (1 matching dictionary)
  1. perniciousness: Legal dictionary

Computing (1 matching dictionary)
  1. perniciousness: Encyclopedia

Medicine (2 matching dictionaries)
  1. perniciousness: Merriam-Webster Medical Dictionary
  2. perniciousness: Medical dictionary

(Note: See pernicious as well.)

Definitions from Wiktionary (perniciousness)

noun:  The condition of being pernicious; destructiveness

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