Usually means: Annoying or frustratingly difficult situation.
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We found 10 dictionaries that define the word pain in the arse:

General (3 matching dictionaries)
  1. pain in the arse: Collins English Dictionary
  2. pain in the arse: Wiktionary
  3. pain in the arse: TheFreeDictionary.com

Business (1 matching dictionary)
  1. pain in the arse: Legal dictionary

Computing (1 matching dictionary)
  1. pain in the arse: Encyclopedia

Medicine (1 matching dictionary)
  1. pain in the arse: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. pain in the arse: Idioms

Slang (3 matching dictionaries)
  1. pain in the arse: Green’s Dictionary of Slang
  2. pain in the arse: English slang and colloquialisms used in the United Kingdom
  3. pain in the arse: Urban Dictionary

Definitions from Wiktionary (pain in the arse)

noun:  (UK, Ireland, Commonwealth, sometimes considered, vulgar) Someone or something that is annoying or frustrating.

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