Usually means: Receptor with unknown natural ligand.
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We found 8 dictionaries that define the word orphan receptor:

General (3 matching dictionaries)
  1. orphan receptor: Wiktionary
  2. Orphan receptor: Wikipedia, the Free Encyclopedia
  3. Orphan receptor: TheFreeDictionary.com

Business (1 matching dictionary)
  1. Orphan receptor: Legal dictionary

Computing (1 matching dictionary)
  1. Orphan receptor: Encyclopedia

Medicine (1 matching dictionary)
  1. Orphan receptor: Medical dictionary

Science (2 matching dictionaries)
  1. Drug Discovery and Development (No longer online)
  2. Orphan receptor: Cytokines & Cells Online Pathfinder Encyclopaedia

Definitions from Wiktionary (orphan receptor)

noun:  (physiology) A receptor that has a similar structure to other identified receptors but whose endogenous ligand has not yet been identified

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