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We found one dictionary that defines the word one-handedness:

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  1. one-handedness: Wiktionary

Definitions from Wiktionary (one-handedness)

noun:  The quality of having a dominant hand; left-handedness or right-handedness.
noun:  Chirality
noun:  The possession of only one hand or the ability to use only one hand; the loss of the use of one hand.
noun:  The state of choosing to use only one hand.
noun:  The quality of being designed for only one hand.
noun:  A state in which only one person is active
noun:  (figurative) Weakness, limitation

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