Usually means: Central point of a problem.
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We found 18 dictionaries that define the word nodus:

General (12 matching dictionaries)
  1. nodus: Merriam-Webster
  2. nodus: Oxford Learner's Dictionaries
  3. nodus: American Heritage Dictionary of the English Language
  4. nodus: Collins English Dictionary
  5. nodus: Wordnik
  6. nodus: Wiktionary
  7. nodus: Webster's New World College Dictionary, 4th Ed.
  8. nodus: Infoplease Dictionary
  9. nodus: Dictionary.com
  10. Nodus: Wikipedia, the Free Encyclopedia
  11. nodus: The Phrontistery - A Dictionary of Obscure Words
  12. nodus: TheFreeDictionary.com

Medicine (3 matching dictionaries)
  1. Dorland's Illustrated Medical Dictionary (No longer online)
  2. online medical dictionary (No longer online)
  3. nodus: Medical dictionary

Science (2 matching dictionaries)
  1. nodus: Dictionary of Botanical Epithets
  2. Glossary of Entomology (No longer online)

Slang (1 matching dictionary)
  1. Nodus: Urban Dictionary

(Note: See nodi as well.)

Definitions from Wiktionary (nodus)

noun:  A difficulty.
noun:  (zoology) In the Odonata, a prominent crossvein near the centre of the leading edge of a wing.

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