Might mean (unverified): Protein linking nucleus to cytoskeleton.
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We found 2 dictionaries that define the word nesprin:

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  1. nesprin: Wiktionary
  2. Nesprin: Wikipedia, the Free Encyclopedia

Definitions from Wiktionary (nesprin)

noun:  (biochemistry) Any of a family of proteins, found in the outer membrane of cell nuclei, that bind to actin or plectin filaments

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