Might mean (unverified): New antigen formed by mutations.
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We found 2 dictionaries that define the word neoepitope:

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  1. neoepitope: Wiktionary
  2. Neoepitope: Wikipedia, the Free Encyclopedia

Definitions from Wiktionary (neoepitope)

noun:  (immunology) A new epitope, or an epitope on a neoantigen

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