Sorry, no online dictionaries contain the exact phrase mysterious substance.
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Reverse dictionary results:
1. enigma
2. mystery
3. unknown
4. ambiguity
5. equivocacy
6. irregularity
7. unclarity
8. unclearness
9. unevenness
10. abearance
11. absurdness
12. ambivalence
13. ambivalent
14. antirationality
15. arbitrariness
16. costlessness
17. differentness
18. dysfunctionality
19. equivocality
20. exceptionality
21. impendency
22. imperceptiveness
23. impercipience
24. imperfection
25. implicity
26. impreciseness
27. inaccuracy
28. incognita
29. incoherency
30. inconspicuousness
31. indecisiveness
32. indefinitude
33. inexplicitness
34. informality
35. insistency
36. instability
37. irrationalness
38. irresoluteness
39. mysterious

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You can look up the words in the phrase individually using these links:   mysterious ?   substance ?
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