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We found 2 dictionaries that define the word mutational meltdown:

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  1. mutational meltdown: Wiktionary
  2. Mutational meltdown: Wikipedia, the Free Encyclopedia

Definitions from Wiktionary (mutational meltdown)

noun:  (genetics) The process by which a small population accumulates harmful mutations, which leads to loss of fitness and decline of the population size, which may lead to further accumulation of deleterious mutations due to fixation by genetic drift.

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