Usually means: Involves multiple synapses between neurons.
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We found 6 dictionaries that define the word multisynaptic:

General (2 matching dictionaries)
  1. multisynaptic: Wiktionary
  2. multisynaptic: Dictionary.com

Medicine (4 matching dictionaries)
  1. multisynaptic: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. online medical dictionary (No longer online)
  4. multisynaptic: Medical dictionary

Definitions from Wiktionary (multisynaptic)

adjective:  Of, pertaining to, or using multiple synapses.

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