Usually means: Highest order bit in binary.
Definitions Related words Mentions
We found 11 dictionaries that define the word most significant bit:

General (5 matching dictionaries)
  1. most significant bit: Oxford Learner's Dictionaries
  2. most significant bit: Wiktionary
  3. Most Significant Bit: Dictionary.com
  4. Most-significant bit, Most significant bit: Wikipedia, the Free Encyclopedia
  5. Most significant bit: TheFreeDictionary.com

Business (1 matching dictionary)
  1. Most significant bit: Financial dictionary

Computing (4 matching dictionaries)
  1. Most Significant Bit: Free On-line Dictionary of Computing
  2. most significant bit: CCI Computer
  3. I T Glossary (No longer online)
  4. most significant bit: Encyclopedia

Medicine (1 matching dictionary)
  1. online medical dictionary (No longer online)

Definitions from Wiktionary (most significant bit)

noun:  (computing) The bit that represents the largest fraction of a value, its position depending on the endianness of the system.

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