Might mean (unverified): Binds one side to membrane.
Definitions Related words Mentions
We found 2 dictionaries that define the word monotopic:

General (2 matching dictionaries)
  1. monotopic: Merriam-Webster
  2. monotopic: Wiktionary

Definitions from Wiktionary (monotopic)

adjective:  Relating to monotopism
adjective:  (biochemistry, of a membrane protein) that interact with only one leaflet of the lipid bilayer
adjective:  (chemistry) That has only one site at which another compound can form a complex

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