Usually means: Direct, single synapse neural connection.
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We found 6 dictionaries that define the word monosynaptically:

General (4 matching dictionaries)
  1. monosynaptically: Merriam-Webster
  2. monosynaptically: Wiktionary
  3. monosynaptically: Dictionary.com
  4. monosynaptically: TheFreeDictionary.com

Medicine (2 matching dictionaries)
  1. monosynaptically: Merriam-Webster Medical Dictionary
  2. monosynaptically: Medical dictionary

(Note: See monosynaptic as well.)

Definitions from Wiktionary (monosynaptically)

adverb:  In a monosynaptic manner; using a single synapse

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