Usually means: One substituent on a molecule.
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We found 5 dictionaries that define the word monosubstituted:

General (3 matching dictionaries)
  1. monosubstituted: Wiktionary
  2. monosubstituted: Infoplease Dictionary
  3. monosubstituted: Dictionary.com

Medicine (2 matching dictionaries)
  1. monosubstituted: Merriam-Webster Medical Dictionary
  2. online medical dictionary (No longer online)

Definitions from Wiktionary (monosubstituted)

adjective:  (chemistry) Having a single substituent

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