Usually means: Color change indicating chemical change.
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We found 3 dictionaries that define the word metachrome:

General (3 matching dictionaries)
  1. metachrome: Merriam-Webster
  2. metachrome: Wordnik
  3. metachrome: Wiktionary

Definitions from Wiktionary (metachrome)

adjective:  Designating dyes and mordants that are applied together.

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