Might mean (unverified): Achieve success through personal effort.
Definitions Related words Mentions
We found 2 dictionaries that define the word make something of oneself:

General (2 matching dictionaries)
  1. make something of oneself: Merriam-Webster
  2. make something of oneself: Wiktionary

Definitions from Wiktionary (make something of oneself)

verb:  (idiomatic) To become successful on one's own initiative.

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