Usually means: Elements in groups 1, 2, 13-18.
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We found 3 dictionaries that define the word main group:

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  1. main group: Wiktionary
  2. Main group: Wikipedia, the Free Encyclopedia

Slang (1 matching dictionary)
  1. Main Group: Urban Dictionary

Definitions from Wiktionary (main group)

noun:  (chemistry) In the periodic table of the elements, any of the eight groups (columns) of elements in the s and p blocks.
noun:  (chemistry, dated) The same, plus the elements of group 12.

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