Usually means: Disease from abnormal prion proteins.
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We found 6 dictionaries that define the word mad cow:

General (3 matching dictionaries)
  1. mad-cow: Wordnik
  2. mad cow: Wiktionary
  3. Mad Cow, Mad cow (disambiguation), Mad cow: Wikipedia, the Free Encyclopedia

Computing (1 matching dictionary)
  1. Mad-cow, Mad cow: Encyclopedia

Medicine (1 matching dictionary)
  1. Mad-cow, Mad cow: Medical dictionary

Slang (1 matching dictionary)
  1. mad cow: Urban Dictionary

Definitions from Wiktionary (mad cow)

noun:  (uncountable, by ellipsis) Mad cow disease; bovine spongiform encephalopathy.
noun:  (countable) A cow afflicted with mad cow disease.
noun:  Used other than figuratively or idiomatically: see mad, cow.

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