Usually means: Organism with a relatively long lifespan.
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We found 7 dictionaries that define the word macrobiote:

General (5 matching dictionaries)
  1. macrobiote: Collins English Dictionary
  2. macrobiote: Wordnik
  3. macrobiote: Wiktionary
  4. macrobiote: Dictionary.com
  5. macrobiote: The Phrontistery - A Dictionary of Obscure Words

Medicine (2 matching dictionaries)
  1. Macrobiote: MedFriendly Glossary
  2. online medical dictionary (No longer online)

Definitions from Wiktionary (macrobiote)

noun:  (rare) One who lives for a long time.

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