Definitions from Wiktionary ()
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▸ adjective: (colloquial) Crazy.
▸ adjective: (Southwestern US) Intoxicated by eating locoweed.
▸ noun: A certain species of Astragalus or Oxytropis, capable of causing locoism.
▸ verb: (transitive) To poison with the loco plant; to affect with locoism.
▸ verb: (transitive, colloquial, by extension) To render insane.
▸ noun: (rail transport, informal) A locomotive.
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