Usually means: Large, domesticated bovine from Asia.
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We found 21 dictionaries that define the word jak:

General (15 matching dictionaries)
  1. jak: Merriam-Webster
  2. jak: Collins English Dictionary
  3. jak: Vocabulary.com
  4. Jak, jak: Wordnik
  5. Jak, jak: Wiktionary
  6. jak: Infoplease Dictionary
  7. jak: Dictionary.com
  8. JAK, Jak (Jak and Daxter), Jak: Wikipedia, the Free Encyclopedia
  9. Jak: Online Plain Text English Dictionary
  10. jak: Webster's Revised Unabridged, 1913 Edition
  11. jak: Rhymezone
  12. Jak: AllWords.com Multi-Lingual Dictionary
  13. jak: FreeDictionary.org
  14. jak: Mnemonic Dictionary
  15. Jak: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. jak: Encyclopedia

Medicine (1 matching dictionary)
  1. online medical dictionary (No longer online)

Miscellaneous (3 matching dictionaries)
  1. JAK: Acronym Finder
  2. JAK: Three Letter Words with definitions
  3. AbbreviationZ (No longer online)

Slang (1 matching dictionary)
  1. JAK: Urban Dictionary

(Note: See jaking as well.)

Definitions from Wiktionary (JAK)

noun:  Alternative form of jack (“the tree Mangifera caesia”) [A coarse mediaeval coat of defence, especially one made of leather.]
noun:  (rare) Alternative form of Jack (male given name) [A unisex given name, also used as a pet form of John or more rarely, Jacob.]
noun:  (biochemistry) Initialism of Janus kinase. [(biochemistry) Any of a family of intracellular non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway.]

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