Usually means: Reduced function of the spleen.
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We found 5 dictionaries that define the word hyposplenism:

General (2 matching dictionaries)
  1. hyposplenism: Wiktionary
  2. hyposplenism: Dictionary.com

Medicine (3 matching dictionaries)
  1. Dorland's Illustrated Medical Dictionary (No longer online)
  2. online medical dictionary (No longer online)
  3. hyposplenism: Medical dictionary

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Definitions from Wiktionary (hyposplenism)

▸ noun:  A reduction in spleen function.

Similar:
hypospleny, hypersplenism, hepatosplenism, autosplenectomy, splenosis, hepatosplenopathy, splenectopia, polysplenia, splenopathy, hepatosplenitis, more...

Opposite:
hypersplenism, splenomegaly

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Similar:
hypospleny, hypersplenism, hepatosplenism, autosplenectomy, splenosis, hepatosplenopathy, splenectopia, polysplenia, splenopathy, hepatosplenitis, more...

Opposite:
hypersplenism, splenomegaly



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