Usually means: Dividing radiation doses into smaller parts.
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We found 8 dictionaries that define the word hyperfractionation:

General (2 matching dictionaries)
  1. hyperfractionation: Dictionary.com
  2. hyperfractionation: Wiktionary

Medicine (6 matching dictionaries)
  1. ABTA Brain Tumor Patients (No longer online)
  2. Breast Cancer Talking Dictionary (No longer online)
  3. online medical dictionary (No longer online)
  4. hyperfractionation: Dictionary of Cancer Terms
  5. hyperfractionation: Medical dictionary
  6. Hyperdictionary (No longer online)

Definitions from Wiktionary (hyperfractionation)

noun:  (radiotherapy) An especially highly divided form of fractionation: the division of a total dose of radiation into many small fractions.

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