Usually means: Enzyme that catalyzes addition of water.
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We found 6 dictionaries that define the word hydratase:

General (2 matching dictionaries)
  1. hydratase: Wiktionary
  2. hydratase: Dictionary.com

Medicine (4 matching dictionaries)
  1. hydratase: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. online medical dictionary (No longer online)
  4. hydratase: Medical dictionary

Definitions from Wiktionary (hydratase)

noun:  (biochemistry) Any enzyme that catalyzes the addition or removal of the elements of water; a hydrase

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