Usually means: Abnormal development of the brain.
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We found 13 dictionaries that define the word holoprosencephaly:

General (4 matching dictionaries)
  1. holoprosencephaly: Wordnik
  2. holoprosencephaly: Wiktionary
  3. holoprosencephaly: Dictionary.com
  4. Holoprosencephaly: Wikipedia, the Free Encyclopedia

Medicine (8 matching dictionaries)
  1. Dorland's Illustrated Medical Dictionary (No longer online)
  2. Holoprosencephaly: MedTerms.com Medical Dictionary
  3. Medical Dictionary (No longer online)
  4. online medical dictionary (No longer online)
  5. Specific Diseases/Disorders (No longer online)
  6. Disorder Index (No longer online)
  7. holoprosencephaly: Medical dictionary
  8. Holoprosencephaly: Drug Medical Dictionary

Science (1 matching dictionary)
  1. Glossary of Genetic Terms (No longer online)

Definitions from Wiktionary (holoprosencephaly)

noun:  (teratology) A congenital disorder involving insufficient division of the lobes of the brain during fetal development, resulting in skull and facial deformities ranging from minor cleft lip problems to cyclopia, in which a single eye develops where the nose would normally be.

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