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We found 2 dictionaries that define the word give it one's best shot:

General (2 matching dictionaries)
  1. give it one's best shot: Oxford Learner's Dictionaries
  2. give it one's best shot: Wiktionary

Definitions from Wiktionary (give it one's best shot)

verb:  (idiomatic) To make one's best effort or attempt; to try as hard as possible.


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