Usually means: Hardening of brain tissue pathology.
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We found 5 dictionaries that define the word encephalosclerosis:

General (2 matching dictionaries)
  1. encephalosclerosis: Dictionary.com
  2. encephalosclerosis: Wiktionary

Medicine (3 matching dictionaries)
  1. Dorland's Illustrated Medical Dictionary (No longer online)
  2. online medical dictionary (No longer online)
  3. encephalosclerosis: Medical dictionary

Definitions from Wiktionary (encephalosclerosis)

noun:  (obsolete, pathology) hardening of brain tissue

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