Usually means: Exchange of segments between chromosomes.
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We found 4 dictionaries that define the word double crossover:

General (2 matching dictionaries)
  1. double crossover: Wiktionary
  2. Double crossover: Wikipedia, the Free Encyclopedia

Computing (1 matching dictionary)
  1. double crossover: Encyclopedia

Medicine (1 matching dictionary)
  1. online medical dictionary (No longer online)

Definitions from Wiktionary (double crossover)

noun:  two pairs of railway switches forming two connections that cross over between two parallel tracks

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