Usually means: Remove froth or scum from.
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We found 8 dictionaries that define the word despume:

General (8 matching dictionaries)
  1. despume: Wordnik
  2. despume: Wiktionary
  3. Despume: Dictionary.com
  4. Despume: Online Plain Text English Dictionary
  5. despume: Webster's Revised Unabridged, 1913 Edition
  6. Despume: AllWords.com Multi-Lingual Dictionary
  7. despume: FreeDictionary.org
  8. Despume: TheFreeDictionary.com

Definitions from Wiktionary (despume)

verb:  (obsolete, transitive) To free from spume, foam or scum.

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