Usually means: Remove someone from friends list.
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We found 10 dictionaries that define the word defriend:

General (10 matching dictionaries)
  1. defriend: Merriam-Webster
  2. defriend: Oxford Learner's Dictionaries
  3. defriend: The Word Spy
  4. defriend: Collins English Dictionary
  5. Defriend, defriend: Wordnik
  6. defriend: Wiktionary
  7. Defriend: Wikipedia, the Free Encyclopedia
  8. defriend: Longman Dictionary of Contemporary English

Definitions from Wiktionary (
)
American English Definition British English Definition
verb:  (social media, uncommon) To remove from one's list of friends (e.g. on a social networking website).

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