Usually means: Enzyme that removes acetyl groups.
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We found 3 dictionaries that define the word deacetylase:

General (2 matching dictionaries)
  1. deacetylase: Wordnik
  2. deacetylase: Wiktionary

Medicine (1 matching dictionary)
  1. deacetylase: Merriam-Webster Medical Dictionary

Definitions from Wiktionary (deacetylase)

noun:  (biochemistry) Any of several classes of enzyme that remove acetyl groups from proteins

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