Usually means: Surgical removal of the gallbladder.
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We found 3 dictionaries that define the word cholecystomy:

General (2 matching dictionaries)
  1. cholecystomy: Wiktionary
  2. cholecystomy: Dictionary.com

Medicine (1 matching dictionary)
  1. online medical dictionary (No longer online)

Definitions from Wiktionary (cholecystomy)

noun:  (surgery) incision into the gallbladder

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