Usually means: Irreversible cessation of all brain activity.
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We found 22 dictionaries that define the word brain dead:

General (16 matching dictionaries)
  1. brain-dead: Merriam-Webster
  2. brain-dead: Oxford Learner's Dictionaries
  3. brain dead: Vocabulary.com
  4. Brain-Dead, Brain-dead, brain-dead: Wordnik
  5. brain-dead: Cambridge Advanced Learner's Dictionary
  6. brain-dead, brain dead: Wiktionary
  7. brain-dead: Webster's New World College Dictionary, 4th Ed.
  8. brain-dead, brain dead: Dictionary.com
  9. Brain Dead (TV series), Brain Dead (album), Brain Dead (band), Brain Dead (disambiguation), Brain Dead, Brain-dead, Brain dead: Wikipedia, the Free Encyclopedia
  10. brain dead: Rhymezone
  11. brain dead: FreeDictionary.org
  12. brain dead: Mnemonic Dictionary
  13. brain-dead, brain dead: TheFreeDictionary.com
  14. brain dead: Longman Dictionary of Contemporary English

Business (1 matching dictionary)
  1. brain dead: Legal dictionary

Computing (2 matching dictionaries)
  1. brain-dead: Free On-line Dictionary of Computing
  2. brain-dead, brain dead: Encyclopedia

Medicine (2 matching dictionaries)
  1. online medical dictionary (No longer online)
  2. brain-dead, brain dead: Medical dictionary

Slang (1 matching dictionary)
  1. Brain-dead, brain dead: Urban Dictionary

Definitions from Wiktionary (Brain dead)

adjective:  Alternative spelling of brain-dead [(medicine, not comparable) Having an irreversible loss of brain function and cessation of brain activity.]

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