Usually means: Substance that inhibits specific function.
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We found 26 dictionaries that define the word blocker:

General (15 matching dictionaries)
  1. blocker: Merriam-Webster
  2. blocker: Oxford Learner's Dictionaries
  3. blocker: Collins English Dictionary
  4. blocker: Vocabulary.com
  5. Blocker, blocker: Wordnik
  6. Blocker, blocker: Wiktionary
  7. blocker: Webster's New World College Dictionary, 4th Ed.
  8. blocker: The Wordsmyth English Dictionary-Thesaurus
  9. blocker: Infoplease Dictionary
  10. blocker: Dictionary.com
  11. Blocker (ice hockey), Blocker: Wikipedia, the Free Encyclopedia
  12. blocker: Rhymezone
  13. blocker: FreeDictionary.org
  14. blocker: Mnemonic Dictionary
  15. blocker: TheFreeDictionary.com

Business (2 matching dictionaries)
  1. blocker: Legal dictionary
  2. blocker: Financial dictionary

Computing (1 matching dictionary)
  1. blocker: Encyclopedia

Medicine (4 matching dictionaries)
  1. blocker: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. online medical dictionary (No longer online)
  4. blocker: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. blocker: Idioms

Slang (2 matching dictionaries)
  1. blocker: Green’s Dictionary of Slang
  2. blocker: Urban Dictionary

Sports (1 matching dictionary)
  1. Hickok Sports Glossaries (No longer online)

(Note: See blockers as well.)

Definitions from Wiktionary (Blocker)

noun:  Agent noun of block (“obstruct or prevent”); something that blocks something else.
noun:  (sports) One who blocks or impedes the movement of an opponent.
noun:  (cricket) A defensive or low-scoring batter.
noun:  (computing) One who prevents another user from contacting them electronically.
noun:  (computing) An application that stops / impedes unauthorised access to a programme.
noun:  (computing) A bug or issue that prevents software from being released.
noun:  (marketing) A gatekeeper who refuses the marketer access to the person they wish to contact.
noun:  (biology, medicine) Any of various medications that block (inhibit) the activity of a chemical messenger or its receptors, such as cardiac conduction modifiers (e.g., alpha-blockers), gastric acid inhibitors (H₂ histamine blockers), puberty blockers, and others.
noun:  A close-fitting rectangular glove worn by a goalie in multiple forms of hockey.
noun:  (poker) A blocker bet.
noun:  (card games) A playing card, needed by one player, that is held by another.
noun:  A person who blocks (stretches or moulds) hats.
noun:  (in combination) A resident or member of a particular block.
noun:  Synonym of block ornament (“a cheap piece of meat of poor quality”). [from 1848]
noun:  A surname.

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