Usually means: Die, fail, or suffer greatly.
Definitions Related words Mentions
We found 4 dictionaries that define the word bite the big one:

General (2 matching dictionaries)
  1. bite the big one: Oxford Learner's Dictionaries
  2. bite the big one: Wiktionary

Miscellaneous (1 matching dictionary)
  1. bite the big one: Idioms

Slang (1 matching dictionary)
  1. American-Australian Slang Dictionary (No longer online)

Definitions from Wiktionary (bite the big one)

verb:  (slang) To die.
verb:  (slang) To break down; to be impossible to repair or not worth repairing.
verb:  (idiomatic) To perform poorly; to fail.
verb:  (slang) To be unpleasant or undesirable.

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