Usually means: Strain or stress over time.
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We found 4 dictionaries that define the word astrain:

General (4 matching dictionaries)
  1. astrain: Merriam-Webster
  2. astrain: Wordnik
  3. astrain: Wiktionary
  4. astrain: Merriam-Webster

Definitions from Wiktionary (astrain)

adjective:  strained or straining

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