Usually means: Trans lunar injection maneuver.
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We found 14 dictionaries that define the word TLI:

General (5 matching dictionaries)
  1. Tli, tli: Wordnik
  2. TLI: Wiktionary
  3. TLI: Dictionary.com
  4. TLI: Wikipedia, the Free Encyclopedia
  5. TLI: Stammtisch Beau Fleuve Acronyms

Computing (3 matching dictionaries)
  1. TLI: Free On-line Dictionary of Computing
  2. BABEL: Computer Oriented Abbreviations and Acronyms (No longer online)
  3. TLI: Encyclopedia

Medicine (2 matching dictionaries)
  1. online medical dictionary (No longer online)
  2. TLI: Medical dictionary

Miscellaneous (2 matching dictionaries)
  1. TLI: Acronym Finder
  2. AbbreviationZ (No longer online)

Slang (1 matching dictionary)
  1. TLI: Urban Dictionary

Tech (1 matching dictionary)
  1. TLI: GEOGRAPHIC INFORMATION SYSTEMS, CARTOGRAPHY, AND REMOTE SENSING

Definitions from Wiktionary (TLI)

noun:  (space science) Initialism of trans-lunar injection. [A maneuver that moves a spacecraft from orbit around the Earth onto a trajectory towards the Moon.]
noun:  (immunology) Initialism of trypsin-like immunoreactivity.

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