Usually means: Aphrodisiac historically made from beetles.
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We found 20 dictionaries that define the word Spanish fly:

General (16 matching dictionaries)
  1. Spanish fly, Spanish fly: Merriam-Webster
  2. Spanish fly: Oxford Learner's Dictionaries
  3. Spanish fly: American Heritage Dictionary of the English Language
  4. Spanish fly: Collins English Dictionary
  5. Spanish fly: Vocabulary.com
  6. Spanish fly: Wordnik
  7. Spanish fly: Wiktionary
  8. Spanish fly: The Wordsmyth English Dictionary-Thesaurus
  9. Spanish fly: Infoplease Dictionary
  10. Spanish fly, spanish fly: Dictionary.com
  11. Spanish Fly (album), Spanish Fly (band), Spanish Fly (instrumental), Spanish fly (disambiguation), Spanish fly, The Spanish Fly (play): Wikipedia, the Free Encyclopedia
  12. Spanish fly: Rhymezone
  13. spanish-fly: Webster's 1828 Dictionary
  14. spanish fly: FreeDictionary.org
  15. spanish fly: Mnemonic Dictionary
  16. Spanish fly: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. Spanish fly (insect), Spanish fly: Encyclopedia

Medicine (3 matching dictionaries)
  1. Spanish fly: Merriam-Webster Medical Dictionary
  2. online medical dictionary (No longer online)
  3. Spanish fly (insect), Spanish fly: Medical dictionary

Definitions from Wiktionary (Spanish fly)

noun:  (uncountable) A supposed aphrodisiac extracted from the beetle Lytta vesicatoria; cantharidin, the active ingredient, a vesicant used as a defence by L. vesicatoria and other blister beetles.
noun:  (countable) The beetle Lytta vesicatoria.

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