Usually means: Made smooth, even, and soft.
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We found 11 dictionaries that define the word Smoothened:

General (11 matching dictionaries)
  1. smoothened: Merriam-Webster
  2. smoothened: Collins English Dictionary
  3. smoothened: Vocabulary.com
  4. smoothened: Wordnik
  5. smoothened: Wiktionary
  6. smoothened: Dictionary.com
  7. Smoothened: Wikipedia, the Free Encyclopedia
  8. smoothened: Rhymezone
  9. smoothened: FreeDictionary.org
  10. smoothened: Mnemonic Dictionary
  11. smoothened: TheFreeDictionary.com

(Note: See smoothen as well.)

Definitions from Wiktionary (smoothened)

noun:  (biochemistry) A transmembrane protein belonging to the group of G protein-coupled receptors that is a key component of the hedgehog signaling pathway.


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